Related Experiment Video
Updated: Mar 27, 2026

Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management
Published on: March 28, 2025
Green LED light has anti-inflammatory effects on burns in rats
Maria H C V Catão1, Roniery O Costa1, Cassiano F W Nonaka1
1Postgraduate Program in Dentistry, State University of Paraíba, Campina Grande, PB Brazil.
Purpose:
The aim of this study was to evaluate the effects of green LED light on inflammatory cells in skin burns: a histological study in rats.
Methods:
In this study, 40 rats were randomly divided into 2 groups: G1 - Control (CTR) and G2 - Green Led (LED). Immediately after injury, green light (60J/cm(2), 10s, λ520 at 550nm) was applied in a timely manner in the four coinciding points of the wound angles and at each point, the amount of 60J/cm (2) with a time of 10s was delivered, totaling 240J/cm(2) per session with 24h intervals until the day before animal sacrifice at 3, 7, 14 and 21 days with a lethal dose of intraperitoneal anesthetic.
Results:
In the histological analysis, animals treated with green LED, from 7 days, showed a significant decrease (p<0.05) in inflammatory cells when compared to control group.
Conclusions:
Green LED light provides an anti-inflammatory effect on skin burns of rats.

