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Visually Evoked Spiking Evolves While Spontaneous Ongoing Dynamics Persist.

Raoul Huys1, Viktor K Jirsa2, Ziauddin Darokhan3

  • 1Centre National de la Recherche Scientifique CerCo UMR 5549, Pavillon Baudot CHU Purpan Toulouse, France.

Frontiers in Systems Neuroscience
|January 19, 2016
PubMed
Summary
This summary is machine-generated.

Visual cortex neurons maintain stable spiking dynamics, with spontaneous and evoked activity controlled by a fixed point attractor. This organization ensures a return to spontaneous states and prevents unwanted state transitions.

Keywords:
cortical dynamicscortical statesneuron network stabilityspike trainsspontaneous activityvisual transients

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Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Visual System

Background:

  • Neurons in the primary visual cortex exhibit spontaneous spiking activity without external stimuli.
  • The relationship between spontaneous and visually evoked neural spiking remains unclear.

Purpose of the Study:

  • To investigate whether visually evoked spiking modifies ongoing cortical dynamics or replaces it.
  • To characterize the stability and dynamics of spontaneous and evoked neural activity in the visual cortex.

Main Methods:

  • Laminar recordings were performed in the ferret primary visual cortex.
  • Spontaneous and visually evoked spiking activity of neurons were analyzed.

Main Results:

  • Neural spiking dynamics remain consistent, controlled by a stable fixed-point attractor for both spontaneous and evoked activity.
  • A threshold (separatrix) separates spontaneous and evoked spiking states, preventing spontaneous activity from easily transitioning to evoked states.
  • Evoked spiking activity returns to the spontaneous state due to the attractor's influence.

Conclusions:

  • The visual cortex maintains stable spiking dynamics, with a fixed-point attractor governing both spontaneous and evoked activity.
  • A threshold mechanism prevents spontaneous activity from propagating and ensures a return to baseline states after visual stimulation.
  • This organization provides functional advantages by avoiding system reorganization and maintaining distinct spontaneous and evoked states.