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Murine Superficial Lymph Node Surgery
Published on: May 21, 2012
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Surgery for Non-Hodgkin's Lymphoma
Elroy Patrick Weledji1, George Enow Orock2
1Department of Surgery, University of Buea , Cameroon, Africa.
Oncology Reviews
|January 19, 2016
Summary
Surgery plays a limited but specific role in managing Non-Hodgkin lymphomas (NHL), aiding diagnosis and palliation. Further research is needed to define optimal surgical timing with other treatments for NHL.
Area of Science:
- Hematology
- Surgical Oncology
Background:
- Non-Hodgkin lymphomas (NHL) are heterogeneous blood cancers.
- Standard treatments include chemotherapy, biological therapy, radiotherapy, and stem cell transplantation.
- Surgery is not a primary treatment for most NHL cases.
Purpose of the Study:
- To review the natural history of NHL.
- To explore the potential role of surgery in NHL management.
Main Methods:
- Literature review of NHL natural history and surgical applications.
- Analysis of surgical indications in specific NHL contexts.
Main Results:
- Surgery can aid diagnosis via biopsy for equivocal radiological findings.
- Surgical removal of symptomatic limited disease or splenectomy for primary splenic lymphoma may be beneficial.
- Emergency abdominal surgery offers palliation and diagnosis for acute NHL complications.
Conclusions:
- Surgery has specific, albeit limited, roles in NHL diagnosis and palliation.
- Optimal perioperative chemotherapy timing for symptomatic organ-limited disease requires further investigation.
- Prospective randomized trials are necessary to establish consensus on surgical management in NHL.
