Related Experiment Video

Updated: Mar 27, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

9.4K

Microaneurysms in renal angiomyolipomas: Can clinical and computed tomography features predict their presence and

J Champagnac1, C Melodelima2, T Martinelli3

  • 1Department of Urinary and Vascular Radiology, Hospices Civils de Lyon, Hôpital Edouard Herriot, 69437 Lyon, France.

Diagnostic and Interventional Imaging
|January 20, 2016
PubMed
Abstract

Insights

Microaneurysms in renal angiomyolipomas (AMLs) are more common in larger AMLs (>40mm) and are significantly larger in ruptured AMLs. Features like TSC/LAM history or RENAL score did not predict microaneurysms in larger AMLs.

Area of Science:

  • Radiology
  • Oncology
  • Nephrology

Background:

  • Renal angiomyolipomas (AMLs) are benign tumors that can present with microaneurysms.
  • Microaneurysms in AMLs are associated with rupture risk.
  • Understanding features predicting microaneurysms is crucial for patient management.

Purpose of the Study:

  • To identify clinical and multidetector computed tomography (MDCT) features associated with microaneurysms in renal AMLs.
  • To evaluate the size of microaneurysms in relation to AML characteristics and rupture status.

Main Methods:

  • Retrospective review of MDCT and digital subtraction angiography (DSA) in 31 patients undergoing embolization for AMLs.
  • Analysis of clinical data including age, gender, history of tuberous sclerosis complex (TSC) or lymphangioleiomyomatosis (LAM).
  • Consensus-based image analysis by two readers to identify and measure microaneurysms.

Main Results:

  • Microaneurysms were absent in AMLs ≤40mm but present in 50% of AMLs >40mm.
  • Microaneurysms were significantly larger in ruptured AMLs (9.5±5.7mm) compared to non-ruptured AMLs (3.9±1.9mm).
  • No significant association was found between microaneurysm presence/size and TSC/LAM history, RENAL score, or fat volume in AMLs >40mm.

Conclusions:

  • Microaneurysms are a feature of larger AMLs (>40mm) and are associated with rupture.
  • Predictive clinical or MDCT features for microaneurysms in larger AMLs were not identified in this study.
  • Further research may be needed to elucidate risk factors for microaneurysm formation in renal AMLs.
Keywords:
Computed tomographyDigital subtraction angiographyMicroaneurysmRenal angiomyolipoma

More Related Videos

Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography03:19

Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography

Published on: June 21, 2024

2.7K
3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography07:01

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

Published on: October 24, 2019

10.4K

Related Concept Videos

Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
461
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
511
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
433
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
633
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
445