Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Candida fungemia].

G Zanetti1, T Calandra, B de Muralt

  • 1Département de médecine interne, Centre hospitalier universitaire vaudois, Lausanne.

Schweizerische Medizinische Wochenschrift
|September 9, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tarlov cyst: A rare cause of posterior mediastinal mass.

Pulmonology·2019
Same author

CT halo sign in pulmonary metastases from a melanoma.

QJM : monthly journal of the Association of Physicians·2018
Same author

Morphological characteristics of the reversed halo sign that may strongly suggest pulmonary infarction.

Clinical radiology·2017
Same author

Universal screening and decolonization for control of MRSA in nursing homes: follow-up of a cluster randomized controlled trial.

The Journal of hospital infection·2017
Same author

High resolution computed tomography of the chest in the evaluation of patients with Birt-Hogg-Dubé syndrome.

Revista portuguesa de pneumologia·2017
Same author

Textiloma: A forgotten diagnosis.

Revista portuguesa de pneumologia·2016
Same journal

Respiratory function test in the case of temporary phrenic nerve contusion, associated with pneumoperitoneum; About the diagnostic value of laparoscopy.

Schweizerische medizinische Wochenschrift·2010
Same journal

Treatment of pulmonary tuberculosis and pleurisy by means of temporary paralysis of the diaphragm, supported by the pneumoperitoneum.

Schweizerische medizinische Wochenschrift·2010
Same journal

Boeck's disease as a tuberculous syndrome.

Schweizerische medizinische Wochenschrift·2010
Same journal

Enteral primary tubercular complexes

Schweizerische medizinische Wochenschrift·2010
Same journal

Tuberculous stenoses of the large bronchi.

Schweizerische medizinische Wochenschrift·2010
Same journal

About the enzyme action.

Schweizerische medizinische Wochenschrift·2010
See all related articles

Nosocomial fungemia, often caused by Candida albicans, is a serious infection. Antifungal treatment significantly reduces mortality in patients with fungemia.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Hospital Epidemiology

Background:

  • Fungemia, a bloodstream infection caused by fungi, poses a significant threat in hospital settings.
  • Candida species are a leading cause of fungemia, particularly in immunocompromised patients.
  • Understanding the epidemiology and outcomes of fungemia is crucial for effective patient management.

Purpose of the Study:

  • To analyze the clinical characteristics, risk factors, and outcomes of fungemia episodes caused by Candida species.
  • To evaluate the impact of antifungal therapy on mortality rates in patients with fungemia.
  • To identify common portals of entry and predisposing conditions associated with fungemia.

Main Methods:

  • Retrospective analysis of 52 fungemia cases due to Candida species from 1980-1986.

Related Experiment Videos

  • Data collection included patient demographics, underlying conditions, prior bacteremia, clinical presentation, and treatment.
  • Statistical analysis compared outcomes between treated and untreated patient groups.

    • Main Results:

    • Fungemia was predominantly nosocomial (98%), occurring after a median hospital stay of 24 days.
    • Candida albicans was the most frequent isolate (71%), with the digestive tract (38%) and intravascular catheters (31%) as common entry points.
    • Patients receiving antifungal therapy (amphotericin B or ketoconazole) had significantly lower global and fungemia-related mortality rates compared to untreated patients (30% vs. 87% and 11% vs. 47%, respectively).

    Conclusions:

    • Nosocomial fungemia is associated with high mortality, particularly in patients with underlying conditions.
    • Prompt and appropriate antifungal therapy is critical for improving survival rates in fungemia patients.
    • Effective infection control measures and early diagnosis are essential to reduce the burden of fungemia in healthcare settings.