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Cutaneous leukocytoclastic vasculitis revealing multifocal tuberculosis
Mariame Meziane1, Nisrine Amraoui1, Harmouch Taoufik2
1Dermatological Department, Hassan II University Hospital, Fes, Morocco.
International Journal of Mycobacteriology
|January 21, 2016
Summary
Cutaneous leukocytoclastic vasculitis (CLV), a rare vascular disorder, can be an early sign of multifocal tuberculosis. Prompt diagnosis and treatment with anti-tuberculous therapy led to rapid improvement in this case.
Area of Science:
- Vascular Medicine
- Infectious Diseases
- Dermatology
Background:
- Cutaneous leukocytoclastic vasculitis (CLV) is an inflammatory vascular condition.
- Associations between CLV and tuberculosis are rarely documented.
Purpose of the Study:
- To report a case where CLV revealed multifocal tuberculosis.
- To highlight Mycobacterium tuberculosis as a potential cause of CLV.
Main Methods:
- Case report of a young male patient.
- Diagnostic confirmation via pleural and perianal biopsy showing tuberculoid granuloma with caseous necrosis.
- Treatment with anti-tuberculous quadritherapy.
Main Results:
- CLV was the initial presentation of multifocal tuberculosis.
- Biopsies confirmed tuberculous infection.
- Rapid clinical improvement was observed following anti-tuberculous treatment.
Conclusions:
- Mycobacterium tuberculosis should be considered in the differential diagnosis of CLV, even when rare.
- Early recognition and treatment of tuberculosis can lead to favorable outcomes in patients presenting with CLV.
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