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Updated: Mar 26, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
[A toddler with an itchy, brown rash]
Karlijn M Mulder1, Maarten H Vermeer
1Leids Universitair Medisch Centrum, afd. Dermatologie, Leiden.
Abstract:
An otherwise healthy 15-month-old boy presented with a pruritic rash that had gradually developed since birth, leaving brown pigmentation. Darier's sign was positive and the diagnosis of juvenile urticaria pigmentosa was made. Juvenile urticaria pigmentosa usually shows spontaneous remission before puberty. Progression to systemic mastocytosis is extremely rare.
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