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Clinical Features, Virus Identification, and Sinusitis as a Complication of Upper Respiratory Tract Illness in

Gregory P DeMuri1, James E Gern1, Stacey C Moyer1

  • 1Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI.

The Journal of Pediatrics
|January 21, 2016
PubMed

Insights

Sinusitis complicates 8.8% of childhood upper respiratory tract illnesses (URIs). Rhinovirus (RV) was the most common virus found in URIs, with RV-A and RV-C linked to illness.

Area of Science:

  • Pediatric infectious diseases
  • Virology
  • Epidemiology

Background:

  • Upper respiratory tract illnesses (URIs) are common in children.
  • Sinusitis is a potential complication of URIs.
  • Understanding the viral causes and incidence of sinusitis in children is important for clinical management.

Purpose of the Study:

  • To determine the incidence of sinusitis complicating URIs in children aged 4-7 years.
  • To identify the clinical, virologic, and epidemiologic characteristics of URIs in this age group.

Main Methods:

  • Observational cohort study in primary care pediatric practices.
  • Prospective identification of URIs in 236 children over one year.
  • Nasal samples analyzed by polymerase chain reaction for 9 respiratory viruses; sinusitis diagnosed using published criteria.

Main Results:

  • Sinusitis was diagnosed in 8.8% of symptomatic URIs.
  • Rhinovirus (RV) was detected in 81% of URIs, with RV-A and RV-C associated with illness.
  • Viruses, particularly RV, were also detected in 33% of asymptomatic children.

Conclusions:

  • Sinusitis complicates approximately 8.8% of childhood URIs.
  • Rhinovirus is the most frequent viral cause of URIs in children, with specific types linked to illness.
  • Viruses are commonly found in asymptomatic children, and most URIs resolve within 10 days.
Abstract

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