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Updated: Jul 31, 2026

10:17
An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
Published on: November 3, 2010
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2nd BASHH Oxford Diagnostics Course, November 2015
R R Patel1, J A White2, A S Menon-Johansson3
11 Walsall Healthcare NHS Trust, Walsall, UK.
International Journal of STD & AIDS
|January 21, 2016
Summary
Rising sexually transmitted infection rates are straining UK sexual health services. This course explored novel remote testing, cost-effective diagnostics like nucleic acid amplification tests, and combating antimicrobial resistance to improve patient care and service efficiency.
Area of Science:
- Sexual health diagnostics
- Public health service design
Background:
- Increasing sexually transmitted infection (STI) rates and demand on UK sexual health services.
- Need for improved patient flow and reduced waiting times in sexual health clinics.
Purpose of the Study:
- To discuss challenges and emerging concepts in diagnostics and service design for sexual health.
- To explore novel remote STI testing strategies and their patient journey, demographics, and uptake.
- To evaluate cost-benefits of diagnostic methods and address antimicrobial resistance.
Main Methods:
- Presentation of various approaches to improve patient flow and reduce waiting times.
- Exploration of remote STI testing, including patient journey and uptake data.
- Cost-benefit analysis of nucleic acid amplification tests versus microscopy/culture for Trichomonas vaginalis detection.
- Discussion on antimicrobial resistance, genotypic markers, and point-of-care testing.
Main Results:
- Novel remote STI testing shows potential for managing patient flow and reaching new demographics.
- Nucleic acid amplification tests offer a cost-effective alternative to traditional methods for Trichomonas vaginalis detection, especially in high-risk groups.
- Antimicrobial resistance is a growing concern, necessitating vigilance and advanced testing methods.
Conclusions:
- Innovative diagnostic and service design approaches are crucial for addressing rising STI rates and service demand.
- Remote testing and advanced diagnostics like NAATs can enhance efficiency and cost-effectiveness in sexual health services.
- Combating antimicrobial resistance requires continuous monitoring and the development of point-of-care resistance tests.
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