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A Hepatocellular Cancer Patient-Derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth
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Undifferentiated Embryonal Sarcoma of Liver
Avyakta Kallam1, Jairam Krishnamurthy2, Jessica Kozel2
1Department of Oncology/Hematology, Creighton University School of Medicine , Omaha, NE.
Rare Tumors
|January 21, 2016
Summary
Undifferentiated embryonal sarcoma of the liver (UESL) is rare. Gemcitabine and docetaxel chemotherapy showed a good response and stable disease in a patient with metastatic UESL, suggesting it as a potential treatment option.
Area of Science:
- Hepatology
- Medical Oncology
- Surgical Pathology
Background:
- Undifferentiated embryonal sarcoma of the liver (UESL) is a rare and aggressive malignant hepatic tumor.
- UESL predominantly affects children and young adults, with rare occurrences in older adults.
- Clinical presentation can be nonspecific, including abdominal pain, weight loss, and gastrointestinal symptoms.
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