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Spinal-generated movement disorders: a clinical review.

Pichet Termsarasab1, Thananan Thammongkolchai2, Steven J Frucht3

  • 1Department of Neurology, Movement Disorder Division, Icahn School of Medicine at Mount Sinai, New York, USA ; Department of Medicine, Neurology Division, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Journal of Clinical Movement Disorders
|January 21, 2016
PubMed
Summary

Spinal-generated movement disorders (SGMDs) encompass a range of conditions affecting spinal cord function. This review details their clinical features and offers practical diagnostic and management strategies for these rare neurological conditions.

Keywords:
Brain deathOrthostatic tremorPainful legs-moving toes syndromeParoxysmal dyskinesiaSpinal cordSpinal myoclonusStiff person syndrome

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Area of Science:

  • Neurology
  • Neuroscience
  • Movement Disorders

Background:

  • Spinal-generated movement disorders (SGMDs) represent a group of rare neurological conditions originating from the spinal cord.
  • These disorders include conditions such as spinal segmental myoclonus, propriospinal myoclonus, and stiff person syndrome.

Purpose of the Study:

  • To provide a comprehensive review of the anatomy and physiology underlying SGMDs.
  • To characterize the clinical features of various SGMDs.
  • To present a practical diagnostic and management approach for these disorders.

Main Methods:

  • Review of relevant anatomical and physiological literature.
  • Clinical characterization of SGMDs.
  • Development of a diagnostic and management framework.

Main Results:

  • Detailed description of the neuroanatomical and physiological basis of SGMDs.
  • Comprehensive overview of the clinical presentations of diverse SGMDs.
  • Outline of a systematic approach to diagnosis and treatment.

Conclusions:

  • SGMDs are a distinct category of movement disorders with spinal origins.
  • Understanding the underlying mechanisms is crucial for accurate diagnosis.
  • A structured approach facilitates effective management of these challenging conditions.