Thrombolysis for Severe Intestinal Ischemia due to Midgut Volvulus in a Neonate

Nouredin Messaoudi1, Koen Vanlede2, Dirk Vervloessem3

  • 1Department of General, Digestive and Pediatric Surgery, Sint-Augustinus Hospital, Wilrijk, Belgium.

Intestinal malrotation complicated by the development of midgut volvulus presents a difficult management dilemma because of the risk of short bowel syndrome. Here, we present our experience with a case of severe intestinal ischemia after derotation in a newborn successfully managed using systemic tissue plasminogen activator. The present report supports the usefulness of thrombolysis as a therapeutic option for reperfusion of ischemic small bowel due to midgut volvulus in neonates.