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Published on: September 9, 2012
Advanced Congestive Heart Failure Associated With Disseminated Intravascular Coagulopathy
Annahita Sarcon1, Xiaoli Liu1, David Ton1
1Scripps Green Hospital, La Jolla, CA, USA.
Insights
Disseminated intravascular coagulopathy (DIC) can arise from severe congestive heart failure, leading to biventricular thrombi. This case highlights an underrecognized association between heart failure and DIC, warranting further investigation.
Area of Science:
- Cardiology
- Hematology
Background:
- Disseminated intravascular coagulopathy (DIC) is a serious complication secondary to underlying conditions like sepsis, trauma, and malignancy.
- The association between DIC and congestive heart failure (CHF) is infrequently documented in medical literature.
Purpose of the Study:
- To report a case illustrating the link between severe congestive heart failure and the development of DIC.
- To emphasize that the connection between CHF and DIC may be underrecognized.
Main Methods:
- Case report presentation.
- Review of clinical findings and diagnostic workup for a patient with severe CHF and subsequent DIC.
Main Results:
- Severe congestive heart failure was identified as the precipitating factor.
- Biventricular thrombi were found, preceding the onset of DIC.
- The patient developed DIC secondary to the cardiac condition.
Conclusions:
- Congestive heart failure can lead to disseminated intravascular coagulopathy, an association that warrants greater clinical recognition.
- Further research is necessary to understand the complex interplay between coagulation factors and the pathophysiology of congestive heart failure.
Abstract:
Background. Disseminated intravascular coagulopathy (DIC) is a complication of an underlying disease and not a primary illness. It is most commonly associated with sepsis, trauma, obstetrical complications, and malignancies. There are very few cases in the literature illustrating the association between DIC and congestive heart failure. Findings. In this report, we present a case of severe congestive heart failure, leading to biventricular thrombi and subsequently DIC. Conclusion. We suggest that the association between congestive heart failure and DIC is an underrecognized one. Congestive heart failure continues to remain a major cause of morbidity and mortality despite advances in medical therapies. Thus far, the precise role of coagulation factors in congestive heart failure is unknown. Further investigations are needed to elucidate the pathophysiology of congestive heart failure and coagulation factors.
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