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AIF Is "Always In Fashion" for T Cells
Marc O Johnson1, Jeffrey C Rathmell1
1Vanderbilt Center for Immunobiology, Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232, USA.
Immunity
|January 21, 2016
Abstract:
AIF has been known to have both apoptotic and metabolic roles. Green and colleagues show that T cells, but not B cells, rely on AIF to maintain mitochondrial electron transport and that metabolic, rather than apoptotic, pathways mediate this dependence.
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