Related Experiment Video
Updated: Feb 16, 2026

A High-throughput Cre-Lox Activated Viral Membrane Fusion Assay to Identify Inhibitors of HIV-1 Viral Membrane Fusion
Published on: August 14, 2018
HIV and Tfh Cells: Circulating New Ideas to Identify and Protect
Ann Chahroudi1, Guido Silvestri2
1Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Abstract:
T follicular helper (Tfh) cells provide crucial support to antigen-specific B cells. In this issue of Immunity, Schultz et al. (2016) report that circulating IL-21-producing CD4(+) T cells are phenotypically, transcriptionally, and functionally similar to lymphoid Tfh cells and that such HIV-specific Tfh cells were increased in RV144 trial vaccine recipients.
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