Noncentrosomal microtubules in C. elegans epithelia
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Updated: Mar 26, 2026

In vivo Assessment of Microtubule Dynamics and Orientation in Caenorhabditis elegans Neurons
Published on: November 20, 2021
Sophie Quintin1, Christelle Gally1, Michel Labouesse2
1Development and Stem Cells Department, IGBMC - CNRS UMR 7104/INSERM U964/Université de Strasbourg, 1 Rue Laurent Fries, Illkirch, 67400, France.
Abstract:
The microtubule cytoskeleton has a dual contribution to cell organization. First, microtubules help displace chromosomes and provide tracks for organelle transport. Second, microtubule rigidity confers specific mechanical properties to cells, which are crucial in cilia or mechanosensory structures. Here we review the recently uncovered organization and functions of noncentrosomal microtubules in C. elegans epithelia, focusing on how they contribute to nuclear positioning and protein transport. In addition, we describe recent data illustrating how the microtubule and actin cytoskeletons interact to achieve those functions.
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