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Are glucose levels, glucose variability and autonomic control influenced by inspiratory muscle exercise in patients
Aso Schein1, Aps Correa2,3, Karina Rabello Casali4
1Exercise Pathophysiology Research Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil. andressasilveiradeoliveira@yahoo.com.br.
Background:
Physical exercise reduces glucose levels and glucose variability in patients with type 2 diabetes. Acute inspiratory muscle exercise has been shown to reduce these parameters in a small group of patients with type 2 diabetes, but these results have yet to be confirmed in a well-designed study. The aim of this study is to investigate the effect of acute inspiratory muscle exercise on glucose levels, glucose variability, and cardiovascular autonomic function in patients with type 2 diabetes.
Methods/Design:
This study will use a randomized clinical trial crossover design. A total of 14 subjects will be recruited and randomly allocated to two groups to perform acute inspiratory muscle loading at 2 % of maximal inspiratory pressure (PImax, placebo load) or 60 % of PImax (experimental load).
Discussion:
Inspiratory muscle training could be a novel exercise modality to be used to decrease glucose levels and glucose variability.
Trial Registration:
ClinicalTrials.gov NCT02292810 .
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