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Hormonal control of renal ammonium metabolism: a review
1Department of Pediatrics, University of Wisconsin School of Medicine, Madison.
Abstract:
Hormonal regulation of renal ammonium production and handling has undergone recent intensive investigation. The relationship between hormone action and ammonium metabolism has been known since the beginning of this century. Hormones may directly affect production or excretion of ammonium. Second messengers have also been shown to effect changes in renal ammonium metabolism. Hormonal control of renal ammonium production and handling may play a role in regulation of acute acid-base metabolism, but its role in chronic acid-base pathophysiological states has yet to be determined.