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Working group reports: evaluation of the evidence to support practice guidelines for nutritional care of preterm
Daniel J Raiten1, Alison L Steiber2, Susan E Carlson3
1Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD; raitend@mail.nih.gov.
Insights
The Pre-B Project evaluated evidence for preterm infant nutrition, identifying research gaps. This work supports developing evidence-based guidelines for high-risk newborns.
Area of Science:
- Neonatal Nutrition
- Evidence-Based Practice
- Pediatric Gastroenterology
Background:
- The nutritional care of preterm and high-risk infants requires evidence-informed guidance.
- Existing knowledge needs to be synthesized to support practice guideline development.
Purpose of the Study:
- To present the current state of knowledge on preterm infant nutrition.
- To support the development of evidence-informed practice guidelines for the nutritional care of preterm infants.
- To identify research gaps and establish a research agenda.
Main Methods:
- The Pre-B Project established four working groups (WGs) focusing on nutrient specifications, enteral feeding, gastrointestinal/surgical issues, and infant feeding standards.
- Working groups identified relevant topics, pinpointed questions suitable for systematic review by the Academy of Nutrition and Dietetics' Evidence Analysis Library (EAL), and proposed research agendas.
- This article summarizes the reports from the four working groups.
Main Results:
- The Pre-B Project identified key themes and research questions across nutrient specifications, enteral feeding, gastrointestinal/surgical issues, and current feeding standards for preterm infants.
- Priority research gaps were identified to inform future systematic reviews and guideline development.
- The project established a foundation for evidence-based nutritional care recommendations.
Conclusions:
- The Pre-B Project's first phase successfully outlined the evidence landscape for preterm infant nutrition.
- The identified research gaps and systematic review topics will guide the development of crucial practice guidelines.
- This initiative is essential for advancing the nutritional care and health outcomes of vulnerable newborns.
Abstract:
The "Evaluation of the Evidence to Support Practice Guidelines for the Nutritional Care of Preterm Infants: The Pre-B Project" is the first phase in a process to present the current state of knowledge and to support the development of evidence-informed guidance for the nutritional care of preterm and high-risk newborn infants. The future systematic reviews that will ultimately provide the underpinning for guideline development will be conducted by the Academy of Nutrition and Dietetics' Evidence Analysis Library (EAL). To accomplish the objectives of this first phase, the Pre-B Project organizers established 4 working groups (WGs) to address the following themes: 1) nutrient specifications for preterm infants, 2) clinical and practical issues in enteral feeding of preterm infants, 3) gastrointestinal and surgical issues, and 4) current standards of infant feeding. Each WG was asked to 1) develop a series of topics relevant to their respective themes, 2) identify questions for which there is sufficient evidence to support a systematic review process conducted by the EAL, and 3) develop a research agenda to address priority gaps in our understanding of the role of nutrition in health and development of preterm/neonatal intensive care unit infants. This article is a summary of the reports from the 4 Pre-B WGs.
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