Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lateralization01:28

Lateralization

1.3K
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cortical Location of Language Function May Differ between Languages While White Matter Pathways Are Similar in Brain Lesion Patients.

Brain sciences·2023
Same author

Establishment of a 3D Model to Characterize the Radioresponse of Patient-Derived Glioblastoma Cells.

Cancers·2023
Same author

Postoperative Communicating Hydrocephalus Following Grade 2/3 Glioma Resection: Incidence, Timing and Risk Factors.

Cancers·2023
Same author

The Impact of ioMRI on Glioblastoma Resection and Clinical Outcomes in a State-of-the-Art Neuro-Oncological Setup.

Cancers·2023
Same author

Opportunities and Alternatives of Modern Radiation Oncology and Surgery for the Management of Resectable Brain Metastases.

Cancers·2023
Same author

Hypofractionated stereotactic radiotherapy (HFSRT) versus single fraction stereotactic radiosurgery (SRS) to the resection cavity of brain metastases after surgical resection (SATURNUS): study protocol for a randomized phase III trial.

BMC cancer·2023

Related Experiment Video

Updated: Mar 26, 2026

Localizing Function-specific Targets for Transcranial Magnetic Stimulation in the Absence of Navigation Equipment
09:30

Localizing Function-specific Targets for Transcranial Magnetic Stimulation in the Absence of Navigation Equipment

Published on: May 23, 2025

1.5K

Language function distribution in left-handers: A navigated transcranial magnetic stimulation study.

Lorena Tussis1, Nico Sollmann2, Tobias Boeckh-Behrens3

  • 1Department of Neurosurgery, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675 Munich, Germany.

Neuropsychologia
|January 22, 2016
PubMed
Summary

Left-handers show a more balanced distribution of language functions across both brain hemispheres compared to right-handers. This study used repetitive navigated transcranial magnetic stimulation (rTMS) to investigate language processing in left-handed individuals.

Keywords:
Cortical mappingLanguageLeft-handednessNavigated brain stimulationObject namingTranscranial magnetic stimulation

More Related Videos

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
09:52

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

9.9K
Neuronavigation-guided Repetitive Transcranial Magnetic Stimulation for Aphasia
08:48

Neuronavigation-guided Repetitive Transcranial Magnetic Stimulation for Aphasia

Published on: May 6, 2016

13.0K

Related Experiment Videos

Last Updated: Mar 26, 2026

Localizing Function-specific Targets for Transcranial Magnetic Stimulation in the Absence of Navigation Equipment
09:30

Localizing Function-specific Targets for Transcranial Magnetic Stimulation in the Absence of Navigation Equipment

Published on: May 23, 2025

1.5K
Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
09:52

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

9.9K
Neuronavigation-guided Repetitive Transcranial Magnetic Stimulation for Aphasia
08:48

Neuronavigation-guided Repetitive Transcranial Magnetic Stimulation for Aphasia

Published on: May 6, 2016

13.0K

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Neurolinguistics

Background:

  • Emerging evidence suggests right hemisphere (RH) involvement in language for left-handers, contrasting with typical left hemisphere (LH) dominance in right-handers.
  • Limited lesion-based data exists for understanding language lateralization in left-handed populations.
  • Investigating hemispheric language distribution is crucial for understanding brain plasticity and individual differences.

Purpose of the Study:

  • To investigate the language distribution in left-handers using a non-invasive brain stimulation technique.
  • To compare the language processing laterality between left-handers and right-handers.
  • To determine if left-handers exhibit a different pattern of hemispheric language dominance.

Main Methods:

  • Repetitive navigated transcranial magnetic stimulation (rTMS) was applied to both the left hemisphere (LH) and right hemisphere (RH) in 15 healthy left-handers.
  • Participants performed an object-naming task during rTMS stimulation.
  • Error rates (ERs) and a laterality score ((LH ER - RH ER) / (LH ER + RH ER)) were calculated and compared to data from right-handers.

Main Results:

  • No significant differences in error rates were found between the LH and RH during the object-naming task in left-handers.
  • Left-handers showed a significantly different laterality score compared to right-handers, indicating a more balanced hemispheric language distribution.
  • The laterality score for left-handers suggested nearly equal language dominance distribution between hemispheres, unlike the LH dominance observed in right-handers.

Conclusions:

  • Left-handers exhibit a more bilateral language representation compared to right-handers.
  • Language dominance in left-handers is more equally distributed across both hemispheres.
  • These findings contribute to understanding neuroplasticity and variations in brain organization for language.