Postcomplexation synthetic routes to dipyrrin complexes
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Updated: Mar 26, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
David Perl1, Sean W Bisset, Shane G Telfer
1MacDiarmid Institute for Advanced Materials and Nanotechnology, Institute of Fundamental Sciences, Massey University, Palmerston North, New Zealand. s.telfer@massey.ac.nz.
Abstract:
We report a postfunctionalization synthetic route to dipyrrin complexes that gives access to a broad range of new complexes. This route involves the coordination of a 5-methylthiodipyrrinato ligand to a metal centre followed by displacement of the thiomethyl moiety by a nucleophile. Using rhenium(I) as a platform and amine nucleophiles, we show how complexes that would be difficult or impossible to synthesize via traditional methods can now be accessed.
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