Related Experiment Video
Updated: Mar 26, 2026

Isolation of Atrial Myocytes from Adult Mice
Published on: July 25, 2019
Mobitz type I atrio-ventricular block in dengue myocarditis, requiring temporary pacing
S de Mel1, R Mowjood2, L Kapuruge2
1Department of Haematology-Oncology, National University Health System, 5 Lower Kent Ridge Road, Singapore 119074, Singapore.
This study reports a rare case of dengue myocarditis causing Mobitz type I atrio-ventricular block requiring cardiac pacing. Early steroid treatment showed promise, suggesting a potential therapeutic role for corticosteroids in managing this condition.
Area of Science:
- Cardiology
- Infectious Diseases
- Electrophysiology
Background:
- Dengue virus infection can lead to cardiac complications, including myocarditis.
- Atrio-ventricular (A-V) block is a recognized, though uncommon, manifestation of myocarditis.
- Mobitz type I A-V block is characterized by progressive lengthening of the PR interval.
Purpose of the Study:
- To report a unique case of dengue myocarditis presenting as Mobitz type I A-V block.
- To highlight the first documented instance of such a patient requiring temporary cardiac pacing.
- To explore the potential efficacy of corticosteroid therapy in managing dengue-associated myocarditis and A-V block.
Main Methods:
- Case report detailing clinical presentation, diagnostic workup, and management of a patient with dengue myocarditis.
- Electrocardiographic (ECG) monitoring to diagnose and assess the severity of atrio-ventricular block.
- Therapeutic intervention with methylprednisolone and temporary cardiac pacing as indicated.
Main Results:
- The patient presented with dengue fever complicated by myocarditis and Mobitz type I A-V block.
- Temporary cardiac pacing was required due to the severity of the atrio-ventricular block.
- Prompt administration of methylprednisolone led to an early positive clinical response.
Conclusions:
- Dengue myocarditis can manifest as significant atrio-ventricular block requiring advanced cardiac support.
- This case represents the first report of dengue-associated Mobitz type I A-V block necessitating cardiac pacing.
- Early administration of steroids may be a beneficial therapeutic strategy for dengue-induced myocarditis and associated conduction abnormalities.
More Related Videos
Related Concept Videos
Dysrhythmias IV: Characteristics of Bradyarrhythmias
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis I: Introduction
Myocarditis III: Medical Management
Diphtheria
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...

