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Atherogenic Index of Plasma (AIP): A marker of cardiovascular disease

Shabnam Niroumand1, Mohammad Khajedaluee2, Majid Khadem-Rezaiyan3

  • 1Resident of Community Medicine, Community Medicine Department, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran. NiroumandS911@mums.ac.ir.

Medical Journal of the Islamic Republic of Iran
|January 22, 2016
PubMed

Insights

Atherogenic Index of Plasma (AIP) is a strong predictor of cardiovascular disease (CVD) risk. This study found significant correlations between AIP and waist circumference, BMI, and physical activity levels, suggesting AIP

Area of Science:

  • Cardiovascular Health
  • Biomarkers
  • Public Health Surveillance

Background:

  • Cardiovascular disease (CVD) accounts for one-third of global deaths, necessitating effective primary prevention strategies.
  • Increasing CVD risk factors worldwide highlight the need for reliable predictive markers.
  • Atherogenic Index of Plasma (AIP) is recognized as a potent indicator for atherosclerosis and coronary heart disease risk.

Purpose of the Study:

  • To assess the correlation between Atherogenic Index of Plasma (AIP) and key cardiovascular risk factors.
  • To evaluate the utility of AIP as a monitoring index for CVD risk in clinical practice.

Main Methods:

  • Cross-sectional study utilizing data from Iran's national non-communicable risk factors surveillance system (2008-2010).
  • Analysis included 1000 participants (500 men, 500 women) with demographic and biochemical data.
  • Statistical methods included Chi-square, Mann-Whitney U, and correlation tests (p <0.05 significance).

Main Results:

  • A significant majority (77.5%) of the study population fell into the increased risk category for CVD based on AIP.
  • AIP demonstrated significant positive correlations with waist circumference (r=0.35, p<0.001) and Body Mass Index (BMI) (r=0.33, p<0.001).
  • AIP showed a significant inverse correlation with physical activity levels (r=-0.09, p<0.01).

Conclusions:

  • Atherogenic Index of Plasma (AIP) is a valuable and practical index for routine monitoring of cardiovascular disease risk.
  • AIP is particularly useful in individuals with co-existing cardiovascular risk factors.
  • The findings support the integration of AIP assessment into everyday clinical practice for CVD risk management.
Abstract

Keywords:
AtherogenCardiovascular DiseaseRisk Factor

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