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Updated: Mar 26, 2026

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
Published on: February 13, 2026
A novel retrieval technique for large colorectal tumors resected by endoscopic submucosal dissection: tumor
Daiki Nemoto1, Yoshikazu Hayashi2, Kenichi Utano1
1Department of Coloproctology, Aizu Medical Center, Fukushima Medical University, Fukushima 969-3492 Japan.
Background And Study Aims:
Endoscopic submucosal dissection (ESD) has been developed to facilitate en bloc resection of large lesions. However, it is laborious to retrieve the large colorectal specimens. We propose a novel retrieval technique using a Valsalva maneuver, known as Tumor Extraction by Defecation (TED).
Case Series:
A total of nine lesions (median size 88 mm, maximum 225 mm; proximal colon three, rectum six) that could not be easily retrieved using net forceps were subsequently removed by TED. The rectum was filled with water through the colonoscope. The patient then strained to evacuate the specimen, facilitated by an almost straight anorectal angle. All specimens were retrieved without fragmentation, within minutes. Histology was assessed appropriately, including an adenoma in two and mucosal cancer in seven. All cut margins were verified to be negative. No adverse events occurred.
Conclusions:
TED is a promising technique for retrieving large colorectal specimens after ESD.
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