[Diurnal dynamics of spatial-temporal organization of lymph nodes]

Experiments, performed on CBA mice demonstrate that all the parameters of lymph nodes of various localization possess a diurnal rhythmicity. Certain lympho-endocrine connections participate in realization of the regional peculiarities of the diurnal rhythms via regulation of redistribution of streams of the migrating lymphoid cells, that form the lymph node structures. There are certain differences in endogenous glucocorticoids action, depending on the level of the motor activity, that determines level of the mast cells activation, value of lymph-formation and blood stream intensity in the drained region. Concrete examples of the diurnal spatial-time organization of functional steps are described in inguinal, mesenteric and bifurcational lymph nodes.