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Updated: Mar 26, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
The use of optical coherence tomography in acute coronary syndrome
Yoshiki Matsuo1, Takashi Kubo1, Takashi Akasaka1
1a Department of Cardiovascular Medicine , Wakayama Medical University , Wakayama , Japan.
Abstract:
Optical coherence tomography (OCT) is an intracoronary imaging modality which utilizes near-infrared light to provide high-resolution cross-sectional in-vivo images of the coronary artery. OCT imaging technique enables detailed evaluation of plaque morphology in patients with acute coronary syndrome and helps to understand the underlying mechanisms including plaque rupture, plaque erosion, and calcified nodule. It is useful to optimize percutaneous coronary intervention, and evaluate vascular response to coronary intervention and pharmacological therapy. Advances in intracoronary OCT and further research on clinical applications have the potential to contribute to a better prognosis in acute coronary syndrome.
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Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

