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Updated: Mar 26, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Ruptured Pneumococcal Aortic Aneurysm Presenting as ST-Elevation Myocardial Infarction: Case Report and Literature
Xiaoyue Mona Guo1, Pramod Bonde2
1Bonde Artificial Heart Laboratory, Yale University School of Medicine, New Haven, Connecticut, USA.
Abstract:
Ruptured mycotic aneurysms occur infrequently in current clinical practice, and a pneumococcal etiology is even more rare. This case report describes a patient who initially presented with catheter lab activation for an acute ST-elevation myocardial infarction, receiving a full Plavix load. She was subsequently found to have a ruptured aortic aneurysm and underwent emergency surgical repair, with intraoperative findings of an aorta seeded with Streptococcus pneumonia. A retrospective evaluation of her history revealed clues of a previous upper respiratory infection and long-standing back pain. The subsequent literature review summarizes presentations and outcomes in previously reported, ruptured pneumococcal aneurysms and describes the relatively common occurrence of aortic conditions masquerading as acute myocardial infarctions. We provide recommendations to help approach similar situations in the future.
Insights
A rare case of ruptured pneumococcal aneurysm mimicked a heart attack. Prompt surgical repair and antibiotic treatment were crucial for survival, highlighting the need for broader differential diagnoses.
Area of Science:
- Cardiology
- Infectious Diseases
- Vascular Surgery
Background:
- Mycotic aneurysms are rare, with pneumococcal etiology being exceptionally uncommon.
- Acute ST-elevation myocardial infarction (STEMI) presentation can mask other serious conditions.
Observation:
- A patient presented with STEMI, leading to cardiac catheterization and Plavix administration.
- The patient was later diagnosed with a ruptured aortic aneurysm, requiring emergency surgery.
- Intraoperative findings revealed the aorta was infected with Streptococcus pneumoniae.
Findings:
- Retrospective analysis identified a history of upper respiratory infection and chronic back pain.
- Literature review confirmed the rarity of ruptured pneumococcal aneurysms and discussed aortic conditions mimicking myocardial infarction.
- This case underscores the importance of considering non-cardiac etiologies in atypical presentations.
Implications:
- Highlights the diagnostic challenge of differentiating ruptured aneurysms from acute coronary syndromes.
- Emphasizes the need for a comprehensive patient evaluation, including history and imaging, in complex cases.
- Provides insights into managing rare infectious aortic aneurysms and preventing misdiagnosis.
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Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

