Developmental Patterning as a Quantitative Trait: Genetic Modulation of the Hoxb6 Mutant Skeletal Phenotype

Claudia Kappen1

  • 1Department of Developmental Biology, Pennington Biomedical Research Center/Louisiana State University System, 6400 Perkins Road, Baton Rouge, Louisiana, 70808, United States of America.

Plos One
|January 23, 2016
PubMed
Summary

Hoxb6 gene controls skeletal patterning at the cervico-thoracic junction. Its function is modulated by genetic factors, establishing skeletal pattern as a quantitative trait influenced by gene interactions.

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