Related Experiment Video
Updated: Mar 26, 2026

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging
Published on: April 11, 2025
A posttraumatic pontomedullary rent with good outcome
Philippe De Vloo1,2, Louis Declerck3, Olivier Stevens4
1Department of Neurosurgery, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium. philippe.devloo@uzleuven.be.
Abstract:
Posttraumatic pontomedullary rents have been described mainly as postmortem histopathological findings in patients who died immediately or within the first hours after trauma. To the best of our knowledge, no long-term survivors of this condition have been described, and those surviving initially were always severely impaired. We present the first patient with this condition and with corresponding lesions on imaging who survived longer than 3 months. Moreover, the patient regained almost complete independence 1 year after the trauma. We briefly discuss the proposed mechanisms of this injury. We conclude that this lesion, when incomplete, is not always lethal and can exceptionally have a good clinical outcome. Prevention of respiratory failure is of utmost importance in these patients.

