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Updated: Mar 26, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Co-infection of Epstein-Barr virus and human papillomavirus in human tumorigenesis
Ying Shi1,2,3, Song-Ling Peng4,5,6, Li-Fang Yang7,8,9
1Cancer Research Institute, Central South University, Changsha, 410078, Hunan, P. R. China. yingshi@csu.edu.cn.
Abstract:
Viral infections contribute to approximately 12% of cancers worldwide, with the vast majority occurring in developing countries and areas. Two DNA viruses, Epstein-Barr virus (EBV) and human papillomavirus (HPV), are associated with 38% of all virus-associated cancers. The probability of one patient infected with these two distinct types of viruses is increasing. Here, we summarize the co-infection of EBV and HPV in human malignancies and address the possible mechanisms for the co-infection of EBV and HPV during tumorigenesis.
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