Related Experiment Video
Updated: Mar 26, 2026

06:01
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
15.7K
A spatio-temporal model for spontaneous thrombus formation in cerebral aneurysms
O Malaspinas1, A Turjman2, D Ribeiro de Sousa3
1Centre Universitaire d׳Informatique, Université de Genève, 7, route de Drize, CH-1227 Switzerland.
Journal of Theoretical Biology
|January 24, 2016
Abstract:
We propose a new numerical model to describe thrombus formation in cerebral aneurysms. This model combines CFD simulations with a set of bio-mechanical processes identified as being the most important to describe the phenomena at a large space and time scales. The hypotheses of the model are based on in vitro experiments and clinical observations. We document that we can reproduce very well the shape and volume of patient specific thrombus segmented in giant aneurysms.

