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Is there cardiac risk in panic disorder? An updated systematic review

Daniela Caldirola1, Koen R Schruers2, Antonio E Nardi3

  • 1Department of Clinical Neurosciences, Hermanas Hospitalarias, Villa San Benedetto Menni Hospital, FoRiPsi, 22032 Albese con Cassano, Como, Italy.

Journal of Affective Disorders
|January 24, 2016
PubMed

Insights

This review suggests a link between panic disorder and cardiac conditions, particularly coronary artery disease. Further research is recommended to explore this association for improved patient outcomes.

Area of Science:

  • Cardiology
  • Psychiatry
  • Systematic Review

Background:

  • The relationship between panic disorder (PD) and cardiac disorders (CDs) requires clarification.
  • Existing research has explored links between PD and coronary artery disease (CAD), arrhythmias, cardiomyopathies, and sudden cardiac death.

Purpose of the Study:

  • To conduct an updated systematic review of the association between panic disorder and cardiac disorders.
  • To synthesize evidence on the relationship between PD and specific cardiac conditions like CAD, arrhythmias, and cardiomyopathies.

Main Methods:

  • Systematic review conducted according to PRISMA guidelines.
  • Searched PubMed and bibliographies for studies published between January 1, 2000, and December 31, 2014.
  • Applied selective inclusion criteria based on psychiatric and cardiac diagnostic methodology.

Main Results:

  • Included 14 studies on CAD, 2 on cardiomyopathies, and 1 on arrhythmias.
  • Evidence supports an association between panic and CAD, including subthreshold panic symptoms.
  • Preliminary data suggest associations between panic, arrhythmias, and cardiomyopathies.

Conclusions:

  • The review supports a relationship between panic disorder and cardiac disorders.
  • Further in-depth investigation into the panic-CD association is highly recommended.
  • Understanding this link can improve the treatment and prevention of cardiac events in PD patients.
Abstract

Keywords:
Cardiac diseaseCardiac riskPanic

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