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What does impedance cardiography add more to the assessment of left ventricular diastolic function in essential
Paweł Krzesiński1, Grzegorz Gielerak1, Adam Stańczyk1
1Department of Cardiology and Internal Diseases, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine, Warsaw, Poland.
Insights
Left ventricular diastolic dysfunction (LVDdf) in hypertensive patients is linked to altered hemodynamics, including reduced stroke index and increased arterial stiffness. Impedance cardiography effectively evaluates these changes, with sex influencing outcomes.
Area of Science:
- Cardiology
- Hypertension Research
- Cardiovascular Physiology
Background:
- Left ventricular diastolic dysfunction (LVDdf) and arterial stiffness are significant predictors of mortality in patients with arterial hypertension.
- Understanding the relationship between diastolic function and hemodynamic parameters is crucial for managing hypertensive individuals.
Purpose of the Study:
- To investigate the association between left ventricular diastolic function and the hemodynamic profile in hypertensive patients.
- To assess the utility of impedance cardiography (ICG) in evaluating these relationships.
Main Methods:
- A study involving 209 hypertensive patients.
- Evaluations included clinical assessment, echocardiography (measuring e', E/A), and impedance cardiography (ICG) to assess stroke index (SI), acceleration index (ACI), velocity index (VI), Heather index (HI), and total arterial compliance.
- Analysis focused on correlations between echocardiographic indices and hemodynamic parameters.
Main Results:
- LVDdf was associated with lower SI, VI, ACI, HI, and higher systemic vascular resistance index (SVRI).
- These associations were more pronounced in males, with significant correlations observed between age, VI, SVRI, and diastolic function indices.
- No significant differences in age, blood pressure, BMI, or sex distribution were found between groups, but sex-specific hemodynamic differences were noted.
Conclusions:
- Impedance cardiography is a valuable tool for assessing impaired left ventricular performance and arterial stiffness in hypertensive patients.
- Sex-specific differences in cardiovascular hemodynamics and ventricular-vascular interactions should be considered in therapeutic strategies for hypertension.
Unlabelled:
Left ventricular diastolic dysfunction (LVDdf) and arterial stiffness are associated with increased mortality in patients with arterial hypertension.
The Aim:
of the study was to evaluate the relation between left ventricular diastolic function and hemodynamic profile assessed by impedance cardiography (ICG).
Material And Methods:
In 209 hypertensives clinical evaluation, echocardiography and ICG were performed to evaluate i.e. septal annulus early diastolic velocity (e'), mitral flow ratio (E/A), stroke index (SI), acceleration index (ACI), velocity index (VI), Heather index (HI), total arterial compliance.
Results:
Left ventricular diastolic dysfunction was associated with lower SI (p=0.049), VI (p=0.002), ACI (p=0.014), HI (p=0.002) and higher SVRI (p=0.004). There were no significant differences in age, blood pressure, BMI, sex distribution. Males with LVDdf characterized with lower SI (p=0.011), VI (p<0.00001), ACI (p=0.0005), HI (p=0.00005) and higher SVRI (p=0.008). No such relevant differences were observed in women. In the analysis of the relations between clinical/hemodynamic features and echocardiographic indices of left ventricular diastolic function the significant correlations were observed in males, the most relevant for: age vs E/A (-0.45; p<0.001), VI vs e' (0.30; p<0.001), VI vs E/A (0.30; p<0.001), and SVRI vs e' (-0.28; p<0.001).
Conclusions:
Impedance cardiography revealed to be useful in the evaluation of impaired left ventricular performance and increased arterial stiffness related to LVDdf in young and middle-aged hypertensives. Sex may influence cardiovascular hemodynamics resulting in slightly different ventricular-vascular interactions that should be considered in therapeutic strategies.
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