Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

630
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
630
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

5.9K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
5.9K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

5.5K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.5K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

4.3K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.3K
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

1.0K
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
1.0K
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

838
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
838

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The impact of symptoms and illness insight on treatment adherence in first-episode psychosis: a one-year follow-up study using therapeutic drug monitoring.

BMC psychiatry·2026
Same author

Achieving equity requires investment in vulnerable populations.

The Lancet. Public health·2026
Same author

Health care personnel under the pressure of COVID-19 - a prospective 2-year cohort study.

Nordic journal of psychiatry·2025
Same author

Alcohol use, daily smoking, clozapine use and psychiatric symptom profile in persons with schizophrenia spectrum disorder.

Nordic journal of psychiatry·2025
Same author

Treatment adherence in first-episode psychosis: A one-year follow-up study comparing self-reported adherence, pharmacy refill data, and therapeutic drug monitoring.

Psychiatry research·2025
Same author

Complement C4 gene copy numbers modulate serum immune protein profiles in patients with first-episode psychosis and healthy controls in a sex-specific manner.

Schizophrenia research·2025

Related Experiment Video

Updated: Mar 26, 2026

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid
06:21

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid

Published on: April 7, 2023

2.3K

Diabetes and Schizophrenia.

Jaana Suvisaari1, Jaakko Keinänen2, Saana Eskelinen3,4

  • 1Mental Health Unit, National Institute for Health and Welfare, P.O.BOX 30, 00271, Helsinki, Finland. jaana.suvisaari@thl.fi.

Current Diabetes Reports
|January 25, 2016
PubMed
Summary
This summary is machine-generated.

People with schizophrenia face a significantly higher risk of developing type 2 diabetes due to lifestyle factors and antipsychotic medications. Early lifestyle interventions are crucial for diabetes prevention in this population.

Keywords:
DiabetesPreventionRisk factorsSchizophreniaTreatment

More Related Videos

Live Images of GLUT4 Protein Trafficking in Mouse Primary Hypothalamic Neurons Using Deconvolution Microscopy
08:47

Live Images of GLUT4 Protein Trafficking in Mouse Primary Hypothalamic Neurons Using Deconvolution Microscopy

Published on: December 7, 2017

10.3K
Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
07:30

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion

Published on: May 10, 2018

9.8K

Related Experiment Videos

Last Updated: Mar 26, 2026

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid
06:21

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid

Published on: April 7, 2023

2.3K
Live Images of GLUT4 Protein Trafficking in Mouse Primary Hypothalamic Neurons Using Deconvolution Microscopy
08:47

Live Images of GLUT4 Protein Trafficking in Mouse Primary Hypothalamic Neurons Using Deconvolution Microscopy

Published on: December 7, 2017

10.3K
Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
07:30

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion

Published on: May 10, 2018

9.8K

Area of Science:

  • Psychiatry
  • Endocrinology
  • Public Health

Background:

  • Individuals with schizophrenia exhibit a 2- to 5-fold increased risk of type 2 diabetes compared to the general population.
  • Common risk factors for type 2 diabetes, including obesity, poor diet, and physical inactivity, are prevalent in schizophrenia patients early in the illness course.
  • Low socioeconomic status and income in schizophrenia patients limit their capacity for healthy lifestyle choices.

Purpose of the Study:

  • To highlight the elevated risk of type 2 diabetes in individuals with schizophrenia.
  • To emphasize the need for integrated lifestyle modification interventions in schizophrenia treatment.
  • To stress the importance of interdisciplinary collaboration for managing type 2 diabetes in schizophrenia patients.

Main Methods:

  • This study is a review of existing literature and clinical observations.
  • Analysis of risk factors associated with schizophrenia and type 2 diabetes.
  • Examination of the impact of antipsychotic medications on metabolic health.

Main Results:

  • Schizophrenia patients have a substantially higher incidence of type 2 diabetes.
  • Antipsychotic medications contribute to increased diabetes risk through weight gain and direct effects on insulin sensitivity.
  • Lifestyle factors and socioeconomic status significantly influence diabetes risk in this group.

Conclusions:

  • Lifestyle modification interventions are essential components of diabetes prevention and management for schizophrenia patients.
  • Effective management of type 2 diabetes in schizophrenia requires close communication and collaboration between psychiatric and medical care teams.
  • Addressing socioeconomic determinants of health is vital for improving metabolic outcomes in individuals with schizophrenia.