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Related Concept Videos

Antifungal Agents01:15

Antifungal Agents

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Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to...
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The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
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Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
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Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
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Active packaging with antifungal activities.

N Nguyen Van Long1, Catherine Joly2, Philippe Dantigny3

  • 1Université de Brest, EA 3882, Laboratoire Universitaire de Biodiversité et Ecologie Microbienne, ESIAB, Technopôle Brest-Iroise, 29280 Plouzané, France.

International Journal of Food Microbiology
|January 25, 2016
PubMed
Summary
This summary is machine-generated.

Active packaging effectively controls fungal spoilage in foods like bread and cheese using essential oils and preservatives. However, efficacy varies with food conditions and packaging material.

Keywords:
ChitosanEssential oilsFoodMouldNanoparticlesNatural productsPackagingPreservatives

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Area of Science:

  • Food Science
  • Microbiology
  • Material Science

Background:

  • Fungal spoilage significantly impacts food shelf-life and safety.
  • Existing reviews lack a comprehensive overview of active packaging for fungal control.
  • Recent advancements necessitate an updated review of antifungal active packaging strategies.

Purpose of the Study:

  • To provide an exhaustive review of active packaging applications for controlling fungal spoilage in foods.
  • To analyze the efficacy of various antifungal agents and packaging materials against molds and yeasts.
  • To discuss the microbiological aspects and influencing factors of active packaging performance.

Main Methods:

  • In vitro and in vivo assessment of antifungal compounds (essential oils, preservatives, natural products, fungicides, nanoparticles, chitosan).
  • Evaluation of active packaging effects on the shelf-life of bread, cheese, fruits, and vegetables.
  • Microbiological analysis sorted by fungal species and discussion of methods and results.

Main Results:

  • Essential oils and preservatives demonstrated varying efficacy against mold growth, with Penicillium species being more sensitive than Aspergillus species.
  • Active packaging effectiveness is highly dependent on food environmental factors (water activity, pH, temperature, NaCl).
  • The nature, size, and application method of films, along with inconsistent antifungal compound release, complicate direct comparisons.

Conclusions:

  • Active packaging presents a viable strategy for controlling fungal spoilage in diverse food products.
  • Optimizing active packaging requires careful consideration of both the antifungal agent and the food's specific environmental conditions.
  • Further research is needed to standardize methods and ensure consistent release of antifungal compounds for predictable efficacy.