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Published on: August 31, 2015
Microcystbiopterins A-E, five O-methylated biopterin glycosides from two Microcystis spp. bloom biomasses
Marina Lifshits1, Dimitri Kovalerchik1, Shmuel Carmeli1
1Raymond and Beverly Sackler School of Chemistry and Faculty of Exact Sciences, Tel Aviv University, Ramat Aviv 69978, Israel.
Abstract:
Five previously undescribed biopterin glycosides, microcystbiopterin A-E, were isolated from the extracts of two bloom materials of Microcystis spp. collected from a fishpond (IL-337) and Lake Kinneret (IL-347), Israel. The structure of the pterins was established by interpretation of their UV, CD, 1D and 2D NMR spectra and HR mass measurements. Microcystbiopterin D is the first heptose containing pterin glycoside to be reported in the literature. Their antimicrobial and cytotoxic properties were evaluated but all were found not active in both assays.
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