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Electrophysiological Measurements and Analysis of Nociception in Human Infants
Published on: December 20, 2011
Ethical issues in neonatal research involving human subjects
1Albert Einstein College of Medicine, Bronx, NY; Department of Pediatrics, Division of Neonatology, Children's Hospital at Montefiore, Bronx, NY.
Abstract:
Research involving critically ill neonates creates many ethical challenges. Neonatal clinical research has always been hard to perform, is very expensive, and may generate some unique ethical concerns. This article describes some examples of historical and modern controversies in neonatal research, discusses the justification for research involving such vulnerable and fragile patients, clarifies current federal regulations that govern research involving neonates, and suggests ways that clinical investigators can develop and implement ethically grounded human subjects research.
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