Related Experiment Video
Updated: Mar 26, 2026
09:47
Author Spotlight: Advancing Mitochondrial Research - mtHyper7 Biosensor for Subcellular Analysis
Published on: June 2, 2023
3.6K
A new ratiometric fluorescent probe for rapid, sensitive and selective detection of endogenous hydrogen sulfide in
Xiao Feng1, Tao Zhang2, Jin-Ting Liu1
1Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China. bxzhao@sdu.edu.cn.
Chemical Communications (Cambridge, England)
|January 26, 2016
Abstract:
We have developed a new ratiometric fluorescent probe composed of a coumarin-merocyanine dyad based on the FRET mechanism. The probe showed clear dual-emission signal changes in blue and red spectral windows upon addition of H2S in a dose dependent manner under a single wavelength excitation. The probe targeted mitochondria with high selectivity and sensitivity toward H2S.
