[Regularities in formation of gamma-induced mutants of Saccharomyces cerevisiae]

As shown by an example of the formation of reversions in the leu2 gene of Saccharomyces cerevisiae, the process of mutant formation after gamma-irradiation is associated with the post-irradiation replication phases. When no DNA replication takes place, the mutants are not formed. The periods of realizing premutation lesions into mutations depend on what cell cycle phase the cells were in when irradiated.