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Updated: Mar 26, 2026

Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
Published on: December 1, 2016
Photosensitizers binding to nucleic acids as anticancer agents
Luigi E Xodo1, Susanna Cogoi1, Valentina Rapozzi1
1Department of Medical & Biological Sciences, University of Udine, 3100 Udine, Italy.
Abstract:
Cationic porphyrins (Prs) and phthalocyanines (Pcs) are strong photosensitizers that have drawn much attention for their potential in photodynamic therapy. These compounds have the interesting property of binding to nucleic acids, in particular G-rich quadruplex-forming sequences in DNA and RNA. In this review, we highlight their potential as anticancer drugs.
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