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Updated: Mar 26, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Year in review: transcatheter aortic valve replacement
Meng-Ta Tsai1, Gilbert H L Tang, Gideon N Cohen
1aDepartment of Surgery, Division of Cardiovascular Surgery, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan bDepartment of Surgery, Westchester Medical Center, Section of Cardiothoracic Surgery, New York Medical College, Valhalla, New York, USA cDivision of Cardiac Surgery, Sunnybrook Health Sciences Center, University of Toronto, Ontario, Canada.
Transcatheter aortic valve replacement (TAVR) is effective for intermediate-risk patients, showing long-term durability. Recent advancements improve safety, efficacy, and patient selection for TAVR.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
Background:
- Transcatheter aortic valve replacement (TAVR) initially focused on high-risk patients.
- Expansion to intermediate and low-risk populations is under investigation.
Purpose of the Study:
- Review recent developments in TAVR.
- Analyze current trends and challenges in TAVR expansion.
Main Methods:
- Review of key clinical trials (PARTNER I, PARTNER II, CHOICE).
- Analysis of national registry data (ADVANCE, German Aortic Valve Registry).
- Evaluation of studies on TAVR complications and newer valve generations.
Main Results:
- Confirmed long-term efficacy and durability of TAVR.
- Demonstrated short-to-mid-term success in intermediate-risk patients.
- Highlighted improved safety and efficacy of newer TAVR valves and techniques like conscious sedation.
Conclusions:
- TAVR is now accepted for intermediate-risk patients.
- Ongoing research addresses TAVR complications and optimizes valve selection.
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