Related Experiment Video
Updated: Mar 26, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Surgical Correction of Nonsyndromic Sagittal Craniosynostosis: Concepts and Controversies
Andrew Simpson1, Alison L Wong, Michael Bezuhly
1From the Division of Plastic and Reconstructive Surgery, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia, Canada.
Abstract:
Sagittal craniosynostosis remains the most common type of isolated craniosynostosis, accounting for nearly half of all nonsyndromic cases. The clinical diagnosis is typically made on the basis of a scaphocephalic head shape and is confirmed by computed tomography or magnetic resonance imaging. The current review examines the major surgical options for correction of isolated sagittal craniosynostosis, including their complications and short- and long-term outcomes. Reconstructive techniques have benefited from advances in perioperative anesthesia monitoring and improved safety of blood transfusion. Although extensive calvarial remodeling is considered safe and may confer greater long-term skull shape correction and decreased neuropsychological sequelae, minimally invasive techniques, such as device-assisted expansion of the cranium continue to increase in popularity. This review underscores the need for additional prospective studies comparing different techniques to determine the optimal reconstructive approach for correction of sagittal craniosynostosis.

