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Updated: Mar 26, 2026

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection
Published on: August 26, 2011
Amygdala activity during autobiographical memory recall as a biomarker for residual symptoms in patients remitted
Kymberly D Young1, Wayne C Drevets2, Jerzy Bodurka3
1Laureate Institute for Brain Research, Tulsa, OK, USA.
Abstract:
We performed a linear regression analysis on demographic, memory performance, and amygdala activity during memory recall on 23 unmedicated participants remitted from major depressive disorder. Amygdala activity during positive memory recall, and the percent of specific positive memories recalled were the variables that explained the most variance in residual depressive symptoms. This model was not significant in control or currently depressed participants. Longitudinal follow up is necessary to assess whether these variables predict relapse.
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