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Updated: Mar 26, 2026

Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness
Published on: August 31, 2016
Does the preference of peripheral versus central venous access in peripheral blood stem cell collection/yield change
Mehmet Hilmi Dogu1, Ali Hakan Kaya2, Ilhami Berber3
1Department of Hematology, Faculty of Medicine, Pamukkale University, Denizli, Turkey.
Abstract:
Central venous access is often used during apheresis procedure in stem cell collection. The aim of the present study was to evaluate whether central or peripheral venous access has an effect on stem cell yield and the kinetics of the procedure and the product in patients undergoing ASCT after high dose therapy. A total of 327 patients were retrospectively reviewed. The use of peripheral venous access for stem cell yield was significantly more frequent in males compared to females (p = 0.005). Total volume of the product was significantly lower in central venous access group (p = 0.046). As being a less invasive procedure, peripheral venous access can be used for stem cell yield in eligible selected patients.
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