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The prevalence of airway problems in children with Down's syndrome

Jane Hamilton1, May Maxime Corazon Yaneza2, William Andrew Clement2

  • 1Medical Student, University of Glasgow, Scotland.

International Journal of Pediatric Otorhinolaryngology
|January 27, 2016
PubMed

Insights

Airway problems are common in children with Down syndrome. This study found laryngo-tracheo-bronchial pathology, especially subglottic stenosis, is more prevalent in this population.

Area of Science:

  • Pediatric Pulmonology
  • Genetics
  • Otolaryngology

Background:

  • Airway disorders frequently affect children with Down syndrome.
  • Understanding the true prevalence of these conditions is crucial for early intervention.

Purpose of the Study:

  • To estimate the population prevalence of airway problems in children with Down syndrome.
  • To report findings from airway endoscopy in a birth cohort.

Main Methods:

  • Retrospective review of 239 children with Down syndrome over 20 years (1993-2013).
  • Analysis of children undergoing airway endoscopy for symptoms like stridor, hoarseness, or intubation difficulties.

Main Results:

  • 39 children (16.3%) underwent airway endoscopy.
  • 33 children (13.8%) had at least one airway diagnosis.
  • Common diagnoses included tracheobronchomalacia and symptomatic subglottic stenosis.

Conclusions:

  • Laryngo-tracheo-bronchial pathology is significantly more common in children with Down syndrome.
  • Subglottic stenosis and tracheal issues are particularly prevalent.
Abstract

Keywords:
AirwayDown'sOtolaryngologyPathologyPrevalenceProblemssyndrome

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