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Flow Cytometric Analysis of Bimolecular Fluorescence Complementation: A High Throughput Quantitative Method to Study Protein-protein Interaction
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Automated analysis of flow cytometry data comes of age

Ryan R Brinkman1,2, Nima Aghaeepour3, Greg Finak4

  • 1British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

Cytometry. Part a : the Journal of the International Society for Analytical Cytology
|January 27, 2016
PubMed
Abstract

No abstract available in PubMed .

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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