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Updated: Mar 26, 2026
Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
Published on: August 4, 2021
Polish experiences with paternal lymphocyte immunization in women with recurrent miscarriages
Hanna Motak-Pochrzest1, Andrzej Malinowski2
1The Opole University of Technology, Faculty of Physical Education and Physiotherapy, Opole, Poland.
Objective:
This study aimed to evaluate the efficacy of PLI and results of subsequent pregnancy in women with RM showing alloimmune response.
Materials And Methods:
Immunological investigations were performed in patients with RM. Subsequently, PLI was administered to 241 patients at their request. Of these, 202 conceived between September 2005 and September 2012.
Results:
Of the 202 women, 169 pregnancies resulted in term delivery; the remaining 33 resulted in subsequent miscarriages (success rate = 83.7%). During seven-years observations of 202 tested individuals, 114 women were pregnant again for the second time and 92 pregnancies of them resulted in the next term delivery (success rate =80.7%).
Conclusions:
Alloimmune background indicated that PLI might improve pregnancy outcome in patients suffering from RM. Long-term monitoring did not reveal any negative effects of PLI on the immunological system in the treated women or newborn babies.
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