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Related Concept Videos

Working Memory01:24

Working Memory

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Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
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Working memory and processing speed training in schizophrenia: study protocol for a randomized controlled trial.

Briana D Cassetta1, Vina M Goghari2

  • 1Clinical Neuroscience of Schizophrenia Laboratory, Administration Building, Department of Psychology, University of Calgary, 2500 University Drive NW, Calgary, AB, T2N 1N4, Canada. bcassett@ucalgary.ca.

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Targeted working memory and processing speed training may improve cognitive functions and daily life for individuals with schizophrenia. This study investigates these cognitive remediation benefits in patients.

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Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Psychiatry

Background:

  • Individuals with schizophrenia exhibit significant cognitive deficits, impacting daily functioning.
  • Cognitive remediation is a growing research area, but optimal training targets remain unclear.
  • Targeting foundational cognitive processes like working memory and processing speed may yield broader benefits.

Purpose of the Study:

  • Investigate near-transfer gains in working memory and processing speed after targeted training in schizophrenia.
  • Assess far-transfer effects on other neurocognitive and social cognitive domains.
  • Evaluate improvements in real-world daily functioning post-training.

Main Methods:

  • Double-blind, randomized controlled trial with 81 schizophrenia patients.
  • Three parallel groups: working memory training, processing speed training, and no-training control.
  • 10-week home-based training (30 min/day, 5 days/week); pre- and post-training assessments.

Main Results:

  • Primary outcomes include near-transfer gains in working memory and processing speed.
  • Secondary outcomes assess far-transfer effects on fluid intelligence and social cognition.
  • Tertiary outcomes measure changes in daily functioning.

Conclusions:

  • This study will elucidate the efficacy of targeted cognitive training for schizophrenia.
  • Findings may inform the development of more effective cognitive remediation strategies.
  • Understanding training mechanisms can enhance cognitive and functional recovery in schizophrenia.