Cutaneous manifestation of atrial myxoma

A left atrial myxoma may present in a manner that diverts attention from its cardiac origin. This case report documents a cutaneous clinical presentation that initially was thought to represent a peripheral vasculitis or connective tissue disease. Biopsy specimens revealed a peripheral arterial myxomatous embolus in the skin, and echocardiogram results were diagnostic for atrial myxoma. Embolic manifestations may occur in up to 40% of cases. We hope that description of this patient will alert others to suspect this tumor in unexplained or peculiar forms of vasculitis and to consider an echocardiogram as part of the diagnostic workup.