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Effects of vitamin D levels on asthma control and severity in pre-school children

A Turkeli1, O Ayaz, A Uncu

  • 1Department of Pediatric Allergy and Immunology, Eskisehir State Hospital, Eskisehir, Turkey. aturkeli1965@hotmail.com.

European Review for Medical and Pharmacological Sciences
|January 28, 2016
PubMed

Insights

Children with asthma have lower vitamin D levels, increasing their risk of poor asthma control and severity. Vitamin D sufficiency is linked to better asthma management in preschoolers.

Area of Science:

  • Pediatrics
  • Immunology
  • Nutritional Science

Background:

  • Asthma and vitamin D deficiency are increasingly prevalent, contributing to significant health issues.
  • Understanding the interplay between vitamin D and childhood asthma is crucial for effective management.

Purpose of the Study:

  • To compare vitamin D levels in preschool children with asthma versus healthy controls.
  • To investigate the association between vitamin D status and asthma control and clinical parameters in young children.

Main Methods:

  • Serum 25(OH)D3 levels were measured in 102 preschool children (1-4 years) with asthma and 102 healthy controls during winter.
  • Asthma control was assessed using GINA guidelines and the TRACK tool.
  • Asthma patients were categorized by vitamin D levels: sufficient, insufficient, and deficient.

Main Results:

  • Children with asthma had significantly lower vitamin D levels (22.64 ng/ml) compared to controls (32.11 ng/ml).
  • Vitamin D sufficiency correlated with fewer asthma exacerbations and better asthma control.
  • Higher frequency of controlled asthma was observed in the vitamin D sufficient group.

Conclusions:

  • Vitamin D deficiency and insufficiency are more common in preschool children with asthma.
  • Lower vitamin D levels are associated with poorer asthma control and increased asthma severity in this age group.
Abstract

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